Anti-cancer properties of ruthenium compounds: NAMI-A and KP1019
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Weak Anti-inflammatory and Anti-cancer Properties of Saffron
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The effects of indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019, or FFC14A), the second ruthenium compound that entered clinical trials, in an in vitro model of tumour invasion and metastasis show that the antitumour effects of this compound might include also the modulation of cell behaviour although its cytotoxicity appears to be predominant over these effects. The compari...
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Small molecule ruthenium complexes show great promise as anticancer pharmaceuticals, but further rational development of these as drugs is stymied by an incomplete understanding of the mechanisms that give rise to markedly different biological behaviour for structurally similar species. X-ray fluorescence imaging at two incident energies was used to reveal the intracellular distribution of Ru i...
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ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2020
ISSN: 0032-5449,1732-2693
DOI: 10.5604/01.3001.0013.8549